Russia Studies Nonwoven Filter Material For Filtering Blood
With the continuous progress of modern medical technology, more and more countries in the world have adopted the method of selectively inputting blood components in medical blood pfusion instead of the whole blood, which can reduce the allergic reaction of patients and improve the utilization efficiency of different components of blood.
In Russia, the application of blood component pfusion is still in its infancy, which only accounts for blood pfusion.
total
5%, there is a huge market potential. Therefore, studying blood components filtration and separation materials has become a new research topic.
The white blood cell filtration and separation material in blood has been studied in the Russian Meishan "viscose" chemical fiber science research center.
The white blood cells needed to be filtered and removed in the blood are 7-15 microns in diameter and 20 microns in a few particles. The remaining blood components, such as red blood cells and platelets, are 2-7 microns in diameter.
The components of blood components should have the following characteristics: suitable pore size, necessary permeability, good hydrophilicity, adequate negative charge on the surface of the filter material, which can help white blood cells be filtered through the corresponding filter holes; when filtering, the media can not be adhered to the filter material; and the filter material has less mechanical damage to the red blood cells and platelets in the blood.
Internationally, the general use of nonwoven materials for blood leukocyte filter materials includes needling, spunlacing, hot-melt, papermaking, electrospinning and so on.
fibre
And viscose fibers, etc., all of them have a certain negative charge.
During filtration, the filtration state is closely related to the size of the filter hole and the bulking degree of the filter material.
The surface density and critical surface penetration of the filter determine the amount of filtration, and whether the particulate matter in the blood will be attached to the filter material. In order to ensure that the particles in the blood pass through the corresponding filter holes, the surface of all fibers should be no less than 10 milli - shaped potential.
White blood cell filters in Russia,
Viscose
Cellulosic filaments, bleached cellulose made from sulphate, and nonwovens made from paper-making can be used effectively. The shortage is the modification of papermaking equipment and the high cost. Under general production conditions, the production of different filter materials and the calculation of work efficiency are complex.
Russia also has non-woven filter materials produced by water needling.
The following is a comparison table of white blood cell filter materials and white blood cell filter technical indicators made by Pall in the world.
The white blood cell filter material of Pall is arranged in 3 different specifications: 20-33 micron, 7-15 micron, and 3-5 micron.
The pore size decreases.
Russian filter material has only one specification.
index | technical requirement | " Pall Filter material | Russian made filter material |
Average fiber diameter Mu M (micron) | 2-20 | 2.6-23 | 5.0-6.0 |
Apparent density (capacity) of materials G/cm Three | 0.2-0.4 | Zero point two zero | Zero point two seven |
Surface density G/ M Two | 20-90 | Nineteen point seven | One hundred and twenty |
Total fiber surface area M Two /g | 0.5-4.0 | - | Three point three seven |
Thickness of nonwoven material Mm | 0.1-1.5 | Zero point zero nine | Zero point four five |
Total capacity of filter holes % | 80-95 | Seventy-six point four | Eighty-two point two |
Average pore size of filter hole Mu M (micron) | 5-7 | 2-20 | Seven point six |
Critical surface penetration DIN /cm | 40-55 | Forty-three | Fifty-one |
electrolyte solution PH= "7.3 Surface negative potential MV Millivolt | negative 10- negative Thirty | negative Twenty-two point three | negative Four point three |
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